TRAILER
PLOT
After booking a boat trip to attend a rave on an island located off the coast of Seattle named "Isla del Morte" ("Island of Death"), two college students, Simon and Greg meet up with three girls: Alicia, Karma, and Greg's girlfriend Cynthia. The five arrive to the dock late and the boat that is supposed to take them to Isla del Morte has already left. Victor Kirk, a boat captain, and his first mate Salish agree to ferry them despite knowing the location when they are offered a huge sum of money to leave fast rather than be inspected.
Arriving at Isla del Morte, they find the rave site ransacked and deserted. Alicia, Karma and Simon leave the site to go find anybody around while Cynthia and Greg stay behind. As Greg and Cynthia are about to engage in sex in a tent, the former leaves to urinate. Alone in the tent, Cynthia is killed by a group of zombies. Meanwhile, Alicia, Karma and Simon find a derelict house and as they attempt to investigate the place, they discover Alicia's ex-boyfriend Rudy, Hugh, and rave dancer Liberty, who inform them of a zombie attack during the event.
The six leave the house to fetch Greg and Cynthia. Meanwhile, the zombies kill Salish when he is alone in the forest.
Alicia, Rudy, Karma, Simon, Liberty and Hugh return to the rave site where they find Greg. A zombified Cynthia comes out from behind a tree and kills Hugh but is killed when Casper, a Coast Guard officer who was tracking Kirk, arrives and shoots her. They form a plan to return to Kirk's boat and leave the island. When they return to the beach they find zombies on Kirk's boat. Casper and Greg leave the group to go find help, but Greg is killed in the forest.
Kirk reveals the island's history; Isla del Morte was home to Castillo Sermano, a Spanish Catholic priest that was banished from Spain in the 15th century for his dark experiments, which the Catholic Church forbade. Castillo murdered the crew of St. Cristobal, the ship that was taking him to the island, enslaved the island's natives, and murdered anyone who visited the place. He then created an immortality serum which he injected himself with, allowing him to live forever and return dead souls to life and support his cause. Kirk leads the group to a spot in the forest where he has hidden a box full of guns and weaponry. Once everyone is armed, they decide to head back to the house only to find the courtyard filled with zombies. Liberty and Casper are killed in the ensuing fight and Alicia, Rudy, Kirk, Karma and Simon manage to take shelter inside the house.
When Kirk is alone, he hears Salish whistling outside. He goes outside and sees Salish now zombified. Kirk sacrifices himself by killing Salish and a bunch of zombies with a stick of dynamite, but the explosion also blows up the entrance to the house. The remaining four lock themselves in a lab inside the house, but the zombies break in. Karma finds a hatch in the floor which she, Alicia and Rudy use to escape. Simon sacrifices himself to kill the zombies by shooting a barrel of gunpowder, blowing up the house and the zombies. Alicia, Rudy and Karma find themselves in tunnels. They make their way through the tunnels, but Karma is killed by zombies as she attempts to hold them off as Rudy and Alicia flee.
Alicia and Rudy are aided out of the tunnels by a mysterious man wearing Greg's face as a mask.
The man is revealed to be Castillo Sermano, who then orders a horde of zombies to restrain Alicia and Rudy in an attempt to kill them and use their flesh for his own purposes. Alicia and Rudy escape Castillo, blowing the tunnels up in the process. Castillo manages to survive the explosion and Alicia gets into a sword fight with him. Castillo impales her heart, and Rudy manages to decapitate him soon after. However, the still-alive headless body of Castillo begins to strangle Rudy.
Alicia, who is barely alive, gets up and crushes the head under her foot, which finally kills him. Although Alicia seemingly dies, she and Rudy are rescued by a team of agents. When the agents ask Rudy to identify himself, he reveals his last name is Curien. The ending narration reveals that Rudy gave Alicia the immortality serum, and they return to Seattle.